FunHunt Server

FunHunt is a classifier of correct protein-protein complex orientations. The input to FunHunt are two possible orientations of a complex. A local docking run is performed on the two complexes using RosettaDock. FunHunt then uses features gathered from these docking runs - representing the local energy landscapes of the orientations, and chooses the near-native orientation among both (assuming that one of the orientations is the near native one).
For more details see the "Overview" section.

Insert a PDB file* for conformation A
Insert a PDB file* for conformation B
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Insert the conservation file** for the first chain
Insert the conservation file** for the second chain

* Files representing the two starting conformations have to be in PDB format, specifically each file have to contain two chains with "TER" after each of them, and the occupancy column of the backbone atoms have to larger than 0.
** Conservation files are the output of the ConSurf server on each of the chains in the complex. These are not mandatory but are recommended.

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